The vision of this project is to develop a modelling framework

Focused on the human musculoskeletal system but designed as a generic platform to address other engineering challenges that involve multi-scale modelling, unobservable states and variables and uncertainty. Find out more

Where are they now?

Iain Hannah, Simulation Engineer for Adidas shares his story about working on MultiSim Find out more

Insigneo Institute for in silico Medicine

The Insigneo Institute for in silico Medicine has been created to achieve the scientific ambition behind the Virtual Physiological Human (VPH), producing a transformational impact on healthcare. Find out more

MultiSim’s PDRA obtains lecturership

Erfan Shahpanbopour tells us how MultiSim helped his speedy career progression from a post-doc to lecturer in just two and a half years! Find out more

Modelathon 2017-Combining experimental and computational research to reduce in vivo testing in a pre-clinical setting

Day 1 Instructions for all participants Symposium on combining experimental and computation research to reduce in vivo testing in a pre-clinical setting A dialogue between clinicians, engineers and modellers. Workshop organiser Professor Damien Lacroix, Chair in Biomedical Engineering, Insigneo Institute, University of Sheffield. Our symposium on day-one explores how multidisciplinary groups (...

MultiSim Explained

The vision of the MultiSim programme is to develop a modelling framework focused on the human musculoskeletal system but designed as a generic platform to addre...

Focus of our Research

The two central ideas that the Frontier Engineering multi-scale project focus on are: a) The development of a novel multi-scale model of the musculoskel...

Insigneo

The Insigneo Institute for in silico medicine is a collaborative initiative between the University of Sheffield and Sheffield Teaching Hospitals NHS Foundation ...

Success in public engagement

As a part of Sheffield’s Festival of Science and Engineering, MultiSim hosted a number of public engagement sessions entitled "Dem bones gonna walk ar...

Programme set to help more under-represented teenagers reach their potential

The Brilliant Club is an award-winning charity that exists to increase the number of pupils from under-represented backgrounds progressing to highly-selective universities. They do this by mobilising the PhD co...

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MultiSim’s collaboration with NC3Rs to reduce animal testing

University of Sheffield's researchers are trying to find ways to reduce animal testing in preclinical trials by using computer models and medical imaging. One application of this technology, also known as in si...

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Journal of Biomechanics: Accuracy of synchrotron based digital volume correlation for bone tissue

MultiSim's Dr Enrico Dall'Ara talks about his paper on the accuracy of synchrotron-based digital volume correlation for bone tissue. His research was featured on the homepage of the Journal of Biomechanics edi...

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Find out how to progress your career as a multiscale PDRA

MultiSim has 12 post-doctoral researchers/research assistants (PDRAs). We interviewed this group to explore how they felt MultiSim has contributed to their professional development so far. The paragraphs below ...

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Our goals and aspirations

Professor Marco Viceconti, Executive Director of Insigneo

“The long term vision of in silico medicine will not be fulfilled without a drastic improvement to our ability to model living organisms from the molecule to the whole body. MultiSim research program represents a quantum leap in this direction.”

Professor Damien Lacroix, Director of MultiSim

“MultiSim wants to bring the most advanced engineering techniques to the service of the patient by working on clinically-ready solutions for the personalisation of healthcare.”