Success at our multi-scale modelling competition

Modelathon 2018 received very positive feedback from our participants. Find out more

Pioneering workshop on the resilience of complex engineering systems hosted at the University of Sheffield

A joint event by MultiSim and the ENCORE network Find out more

Insigneo Institute for in silico Medicine

The Insigneo Institute for in silico Medicine has been created to achieve the scientific ambition behind the Virtual Physiological Human (VPH), producing a transformational impact on healthcare. Find out more

An introduction to our research

Focused on the human musculoskeletal system but designed as a generic platform to address other engineering challenges that involve multi-scale modelling, unobservable states and variables and uncertainty. Find out more

Background

MultiSim is a £6.7 million EPSRC Frontier Engineering Award project based at the University of Sheffield's Insigneo Institute for in silico Medicine. This five year multidisciplinary project started on 1st September 2013 involving academics from the Faculty of Engineering and the Faculty of Medicine, Dentistry and Healthcare. MultiSim's vision is to develop a modelling framework focused on the h...

New study improves monitoring of treatments for multiple sclerosis

Pioneering research in Multiple Sclerosis collects patient data under ‘real life’ conditions to improve monitoring of treatments and disease progression O...

Professional development for researchers

MultiSim has 12 post-doctoral researchers/research assistants (PDRAs). We interviewed this group to explore how they felt MultiSim has contributed to their prof...

Collaboration with NC3Rs to reduce animal testing

University of Sheffield's researchers are trying to find ways to reduce animal testing in preclinical trials by using computer models and medical imaging. On...

Dr Enrico Dall’Ara elected to the board of UK VPH Institute Chapter

Congratulations to Dr Enrico Dall’Ara on his election to the board of the UK Chapter of the Virtual Physiological Human (VPH) Institute. ...

Variability in strain distribution in the mice tibia loading model: A preliminary study using digital volume correlation

The study of bone remodeling, how bone tissue changes over time due to the activity of bone cells, is fundamental for the better understanding of musculoskeletal diseases and to design new treatme...

View

Comparison of HR-pQCT- and microCT-based finite element models

The bedrock of developing robust Virtual Physiological Human is a robust and accurate digital transformation of existing medical procedures. The development of high-resolution imaging systems such as HR-pQCT ...

View

MultiSim’s research on the strength of children’s bones could help in the design of safer car seats

New research from MultiSim's academics based at Insigneo and Sheffield Children's hospitals looks into the strength of children's bones which could help in the design of safer car seats. The first study of...

View

View All

Our goals and aspirations

Dr Enrico Dall'Ara, MultiSim Work Package Leader

“The goal of Multisim is to combine experimental, imaging and computational approaches to improve current preclinical and clinical assessment of musculoskeletal diseases and to optimise treatments for patients”

Dr Claudia Mazzà , Director of MultiSim

“MultiSim wants to bring the most advanced engineering techniques to the service of the patient by working on clinically-ready solutions for the personalisation of healthcare.”