Success at our multi-scale modelling competition


Modelathon 2018 received very positive feedback from our participants. Find out more


1st EPSRC MultiSim Interdisciplinary Workshop on Multiscale Modelling


29th March 2019, from 12 - 5 pm

ICOSS Conference Centre, University of Sheffield

Information and Registration


Insigneo Institute for in silico Medicine


The Insigneo Institute for in silico Medicine has been created to achieve the scientific ambition behind the Virtual Physiological Human (VPH), producing a transformational impact on healthcare.  Find out more


An introduction to our research


Focused on the human musculoskeletal system but designed as a generic platform to address other engineering challenges that involve multi-scale modelling, unobservable states and variables and uncertainty. Find out more


Background

MultiSim is a £6.7 million EPSRC Frontier Engineering Award project based  at the University of Sheffield's Insigneo Institute for in silico Medicine. This five year multidisciplinary project started on 1st September 2013, and extended until 1st September 2019, involving academics from the Faculty of Engineering and the Faculty of Medicine, Dentistry and Healthcare. MultiSim's vision is to develop ...

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Publications: find out more about our research

Poroelastic Modeling of Highly Hydrated Collagen Hydrogels: Experimental Results vs. Numerical Simulation with Custom and Commercial Finite Element Solvers

Poroelastic Modeling of Highly Hydrated Collagen Hydrogels: Experimental Results vs. Numerical Simulation with Custom and Commercial Finite Element Solvers

With the non-stop advances in computational methods and tools, researchers have a wide range of possibilities when it comes to choosing the most appropriate software for their work. In the field of biom...
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Image-based Kinematic Ankle Models for Children affected by Juvenile Idiopathic Arthritis

Image-based Kinematic Ankle Models for Children affected by Juvenile Idiopathic Arthritis

Image-based Kinematic Ankle Model This study, carried on as part of the MD-PAEDIGREE project, presents an innovative application for kinematic ankle models, used here to understand possible disease-specific...
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Variability in strain distribution in the mice tibia loading model: A preliminary study using digital volume correlation

Variability in strain distribution in the mice tibia loading model: A preliminary study using digital volume correlation

  The study of bone remodeling, how bone tissue changes over time due to the activity of bone cells, is fundamental for the better understanding of musculoskeletal diseases and to design new treatme...
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Our goals and aspirations

Dr Enrico Dall'Ara, MultiSim Work Package Leader
“The goal of Multisim is to combine experimental, imaging and computational approaches to improve current preclinical and clinical assessment of musculoskeletal diseases and to optimise treatments for patients”
Dr Claudia Mazzà , Director of MultiSim
“MultiSim wants to bring the most advanced engineering techniques to the service of the patient by working on clinically-ready solutions for the personalisation of healthcare.”