Success at our multi-scale modelling competition


Modelathon 2018 received very positive feedback from our participants. Find out more


Pioneering workshop on the resilience of complex engineering systems hosted at the University of Sheffield


A joint event by MultiSim and the ENCORE network Find out more 


Insigneo Institute for in silico Medicine


The Insigneo Institute for in silico Medicine has been created to achieve the scientific ambition behind the Virtual Physiological Human (VPH), producing a transformational impact on healthcare.  Find out more


An introduction to our research


Focused on the human musculoskeletal system but designed as a generic platform to address other engineering challenges that involve multi-scale modelling, unobservable states and variables and uncertainty. Find out more


Background

MultiSim is a £6.7 million EPSRC Frontier Engineering Award project based  at the University of Sheffield's Insigneo Institute for in silico Medicine. This five year multidisciplinary project started on 1st September 2013 involving academics from the Faculty of Engineering and the Faculty of Medicine, Dentistry and Healthcare. MultiSim's vision is to develop a modelling framework focused on the h...

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Publications: find out more about our research

Variability in strain distribution in the mice tibia loading model: A preliminary study using digital volume correlation

Variability in strain distribution in the mice tibia loading model: A preliminary study using digital volume correlation

  The study of bone remodeling, how bone tissue changes over time due to the activity of bone cells, is fundamental for the better understanding of musculoskeletal diseases and to design new treatme...
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Comparison of HR-pQCT- and microCT-based finite element models

Comparison of HR-pQCT- and microCT-based finite element models

The bedrock of developing robust Virtual Physiological Human is a robust and accurate digital transformation of existing medical procedures. The development of high-resolution imaging systems such as HR-pQCT ...
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MultiSim’s research on the strength of children’s bones could help in the design of safer car seats

MultiSim’s research on the strength of children’s bones could help in the design of safer car seats

New research from MultiSim's academics based at Insigneo and Sheffield Children's hospitals looks into the strength of children's bones which could help in the design of safer car seats. The first study of...
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Our goals and aspirations

Dr Enrico Dall'Ara, MultiSim Work Package Leader
“The goal of Multisim is to combine experimental, imaging and computational approaches to improve current preclinical and clinical assessment of musculoskeletal diseases and to optimise treatments for patients”
Dr Claudia Mazzà , Director of MultiSim
“MultiSim wants to bring the most advanced engineering techniques to the service of the patient by working on clinically-ready solutions for the personalisation of healthcare.”