Precision of Digital Volume Correlation Approaches for Strain Analysis in Bone Imaged with Micro-Computed Tomography at Different Dimensional Levels

University of Sheffield's researchers are improving the assessment of deformation in bone tissue using "Digital Volume Correlation" (DVC) approach that is considered a state-of-the-art image-processing technique. This research aims to improve our knowledge about bone fracture mechanism. Particularly focusing on the bone fracture mechanism due to bone and joint diseases su...
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A new proxy measurement algorithm with applications to vertical ground reaction forces with wearable sensors

A proxy measurement is commonly used when direct measures of the outcome are unobservable and/or unavailable. This paper is a typical and successful application of proxy measurement strategy. In this particular application, wearable IMU (Inertia Measurement Unit) sensors were used to measure the accelerations at different body levels. The acceleration signals were used as the p...
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Michael Woodward

Michael is completing his 'Year in Industry' placement with Insigneo between the second and third year of his undergraduate degree in Bio Engineering at the University of Sheffield. He was previously a part of the Insigneo Summer Student Placement Programme where he was introduced to the field of multi-scale modelling.  His role as Research Support Assistant in musculoskele...
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Fine tuning scan time for improving preclinical assessment of bone tissue

  MultiSim’s researchers are trying to find ways to reduce and refine animal testing in pre-clinical trials by using computer models and medical imaging.  One application of these approaches is to study the effect of skeletal diseases such as osteoporosis and its treatments. At the University of Sheffield, high-resolution scans can be performed on mice to measure...
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Barbara Kalkman

Barbara completed a masters in research (Human Movement Sciences) at the VU University, Netherlands. Her masters dissertation focused on neuro-muscular control of cross-educated movements. In 2014 she started a PhD at Liverpool John Moores University. Her doctoral research based in the University's Biomechanics group focused on muscle mechanical properties and the response...
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PhDs help teenagers reach their potential

The Brilliant Club is an award-winning charity that exists to increase the number of pupils from under-represented backgrounds progressing to highly-selective universities. They do this by mobilising the PhD community to share its academic expertise with state schools. Ana Sofia Ferreira,  a PhD student on the MultiSim project at the University of Sheffield’s Insigneo In...
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My professional development at MultiSim: Mario Giorgi

Mario Giorgi, shares his journey of professional development as a post-doctoral researcher on the MultiSim project based at the University of Sheffield's Insigneo Institute for in silico Medicine.  "I joined Insigneo in July 2015 on the Multisim Frontier Grant, and have now been a part of this amazing group for almost two years. Before joining MultiSim, I knew that this proj...
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Preclinical assessment of bone health

Dr. Enrico Dall'Ara  presented a seminar on Preclinical assessment of bone health with longitudinal imaging and finite element modelling at INSERM institute, Lyon, France. His session was hosted by Prof Philippe Clezardin and Dr Helene Follet. Dr Dall'Ara joined the University of Sheffield in 2013 in the Department of Mechanical Engineering. His research focuses on a better ...
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Success at tackling multi-scale problems: Modelathon 2017

The MultiSim Modelathon 2017 took place 11 – 14 September 2017 at the Diamond Building, Sheffield and aimed to provide an opportunity to discuss, network, and practise multi-scale research modelling skills through a hackathon competition with industry software and hands-on support from modelling experts. Modelathon 2017 was attended by 26 multi-scale researchers from a number o...
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