Focus of our Research

The two central ideas that the Frontier Engineering multi-scale project focus on are: a)      The development of a novel multi-scale model of the musculoskeletal system that describes the mechanobiological processes from the whole body (neuromuscular control and body dynamics) down to the cellular level (bone remodelling and mechanosensing); b)      The creation of a mult...
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Insigneo

The Insigneo Institute for in silico medicine is a collaborative initiative between the University of Sheffield and Sheffield Teaching Hospitals NHS Foundation Trust. It is a multi-disciplinary institute involving over 130 academics and clinicians who collaborate to develop computer simulations of the human body and its disease processes that can be used directly in clinical pr...
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Our vision

The vision of the MultiSim programme is to develop a modelling framework focused on the human musculoskeletal system but designed as a generic platform to address other engineering challenges that involve multi-scale modelling, unobservable states and variables, and uncertainty. This project aims to create a new generation of predictive models capable of handling complex mul...
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Workshop outcomes

The first MultiSim workshop The first MultiSim workshop was aimed at UK academics, clinicians and industry interested in the multiscale modelling of the neuromusculoskeletal system. The event was structured to generate an open discussion forum to map the issues, challenges and opportunities in this research area. The vision of the ambitious MultiSim programme is to develop a ...
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