Modelathon 2017-Combining experimental and computational research to reduce in vivo testing in a pre-clinical setting

Day 1 Instructions for all participants
Symposium on combining experimental and computation research to reduce in vivo testing in a pre-clinical setting
 A dialogue between clinicians, engineers and modellers.
Workshop organiser Professor Damien Lacroix, Chair in Biomedical Engineering, Insigneo Institute, University of Sheffield. 

Our symposium on day-one explores how multidisciplinary groups (clinicians, engineers and modellers) can combine experimental and computational research methods in a cost and time effective way to reduce in vivo testing in a pre-clinical setting. The computational methods discussed at our event may be applied to human trials as well.  To help us coordinate our group discussion, on registration, please let us know of any topics you would like covered.
Using mice as a working model we aim to start off dialogues and collaborations across disciplines through a roundtable discussion, expert keynotes, posters, and three-minute researcher’s presentations. Poster presentations and/or three-minute short presentation about your research are optional.

Poster guidelines

  • Please report to the registration desk on arrival. Poster presenters are required to have their posters in place by 10:15 ( Workroom 3, Level 2)  on the day.
  • Your posters should be A1 size.
  • You will need to print your posters yourself.
  • You will be provided with material to secure your poster to the board at registration.
  • Please be at your poster during breaks and during the lunch breaks (after you have lunch of course!)
  • At 17:00, please pack your poster and take it with you – there are no overnight storage facilities available. Any posters left over will be discarded.
    Participants who are staying in overnight accommodation please take your posters down to the reception where they will be stored with your luggage.
Three-minute talk guidelines 
For three minute presentations, the use of PowerPoint is optional. If you are using a PowerPoint you will need to bring your presentation on your own memory stick.
Please note that you will be presenting to an audience of about 50-60 people.

Day 1 only delegates: Agenda & joining instructions:

 

DAY 1 only participants Modelathon Agenda online 22.8.17
Two pages in total.  Please click the arrow on the bottom left-hand corner to view the next page.

 

Day 1-4 delegates: Agenda & joining instructions

Five pages in total. Please click the arrow on the bottom left-hand corner to view the next page. 

Day 1-4 participants Modelathon Agenda online 08.09.17

Modelathon competition

Days 2-4

The competition is based on the concept of a hackathon where different teams work on a challenging problem to ‘hack’ computer code. This event, however, uses ‘modelling’ and ‘simulation’ rather than ‘hacking’.  Our modelling competition on days 2-4 is supported by leading companies such as Ansys, Dassault SystemesSynopsys and Materialise, who will each provide hands-on support by sending an expert for the duration of the event to ensure participants utilise their company’s software to its full potential in a competitive environment.

Experience working in a team of  multi-scale professionals 

As a MultiSim Modelathon participant, you will be joining the brightest PhD and post-doctoral researchers in the field of multi-scale modelling and biomechanical engineering from around the world. Participants will be grouped into teams to try and solve a complex multi-scale modelling problem. These teams will compete against one another in front of industry and academic experts to find a solution to the assigned problem. By utilising computer simulations, participants will compete to find quicker and more effective methods of addressing musculoskeletal and cardiovascular diseases.

This is an ideal opportunity to:

  • gain practical experience of working with professionals in a multi-scale research modelling team that is likely to include clinicians and modellers;
  • enhance your computer simulation skills by using technical software on challenges based on the subject of multi-scale biomechanics in front of industry and academic experts;
  • have access to state-of-the-art techniques and software (including Abaqus, Ansys, Simpleware, Mimics, Matlab and OpenSim) as your team works through this  multi-scale challenge;
  • network and make friends in your research area;
  • win Amazon gift vouchers of £100 as a member of the winning team!

This year the challenges will be based around producing a murine in silico model to look at the effects of loading and angiogenesis on the healing process in bones. The starting point for these challenges are CT and MRI images of a mouse. Participants will gain a deeper insight into building musculoskeletal models, finite element and cardiovascular models from personalised clinical data.

Background

 An overview of our event

Our four-day EPSRC ‘MultiSim* Modelathon’ event brings together the very best of theory and practice in the area of multi-scale modelling. After two successful events, we have added an additional day that takes the format of a symposium on day-one. This is followed by a three-day multi-scale modelling competition. Our symposium can be attended as a standalone event or as a pre-session for our modelling competition.

All respondents to our last event survey said they would recommend this event to their friends! 
Dr Peter Eltes, a member of the winning team in 2016 and a medical researcher at the National Centre for Spinal Disorders in Hungary, commented:

‘I feel this event simulates a real world experience of finding a solution to a clinical problem where people from a diverse academic background would provide different perspectives. I feel this atmosphere played an enormous role in the creative part of the problem-solving process! The support provided by the MultiSim IT group and the software companies was very helpful.’ 

Industrial participation

Modelathon 2016 was attended by Ansys, Dassault Systemes, Synopsys and Materialise.  Our partners provided hands-on support by sending an expert for the duration of the event to ensure participants utilise their company’s software to its full potential in a competitive environment.

MultiSim*

The MultiSim project is an Engineering and Physical Sciences Research Council (EPSRC) funded programme awarded to the University of Sheffield to develop a multiscale modelling framework of the human musculoskeletal system. MultiSim aims to generate computer simulations that help diagnosis and provide patient-specific treatment recommendations. In addition, to saving time and money, the new computer tools will provide a more reliable diagnosis of the disease, a better treatment, and a detailed prognosis and monitoring of the treatment. The final goal of such a programme is to improve patient’s quality of life. As a part of the MultiSim programme each year we hold a competition called the Modelathon our last event was held in September 2016 at the University of Sheffield.

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