Modelathon 2017-Combining experimental and computational research to reduce in vivo testing in a pre-clinical setting

Register for MultiSim’s Modelathon 2017 an EPSRC funded symposium followed by a three-day modelling competition on combining experimental and computational research to reduce in vivo testing in a pre-clinical setting

Date Monday – Thursday, 11-14 September 2017, Diamond Building, University of Sheffield
Audience Researchers in biomechanics, computational modelling or image based solutions
Purpose An opportunity to discuss, network, and practise multi-scale research modelling skills through a hackathon competition with industry software and hands- on support from modelling experts including Ansys, Dassault Systemes, Synopsys and Materialise
Win prizes Members of the winning team will each receive a £100 Amazon gift voucher
Register at our online store by 20 August 2017. Places limited to 80 participants.

Supported by

Background

An overview of our event

Our four-day EPSRC ‘MultiSim* Modelathon’ event brings together the very best of theory and practice in the area of multi-scale modelling. After two successful events, we have added an additional day that takes the format of a symposium on day-one. This is followed by a three-day multi-scale modelling competition. Our symposium can be attended as a standalone event or as a pre-session for our modelling competition. (More information below image gallery) Our event is supported by:

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All respondents to our last event survey said they would recommend this event to their friends! 
Dr Peter Eltes, a member of the winning team in 2016 and a medical researcher at the National Centre for Spinal Disorders in Hungary, commented:

‘I feel this event simulates a real world experience of finding a solution to a clinical problem where people from a diverse academic background would provide different perspectives. I feel this atmosphere played an enormous role in the creative part of the problem-solving process! The support provided by the MultiSim IT group and the software companies was very helpful.’ 

 

Industrial participation

Modelathon 2016 was attended by Ansys, Dassault Systemes, Synopsys and Materialise.  Our partners provided hands-on support by sending an expert for the duration of the event to ensure participants utilise their company’s software to its full potential in a competitive environment.

MultiSim*

The MultiSim project is an Engineering and Physical Sciences Research Council (EPSRC) funded programme awarded to the University of Sheffield to develop a multiscale modelling framework of the human musculoskeletal system. MultiSim aims to generate computer simulations that help diagnosis and provide patient-specific treatment recommendations. In addition, to saving time and money, the new computer tools will provide a more reliable diagnosis of the disease, a better treatment, and a detailed prognosis and monitoring of the treatment. The final goal of such a programme is to improve patient’s quality of life. As a part of the MultiSim programme each year we hold a competition called the Modelathon our last event was held in September 2016 at the University of Sheffield.

Programme

Day 1
Symposium on combining experimental and computation research to reduce in vivo testing in a pre-clinical setting – A dialogue between clinicians, engineers and modellers 

Our symposium on day-one explores how multidisciplinary groups (clinicians, engineers and modellers) can combine experimental and computational research methods in a cost and time effective way to reduce in vivo testing in a pre-clinical setting. The computational methods discussed at our event may be applied to human trials as well.  To help us coordinate our group discussion, on registration, please let us know of any topics you would like covered.
Using mice as a working model we aim to start off dialogues and collaborations across disciplines through a roundtable discussion, expert keynotes, posters, and 3-minute researcher presentations.

Poster presentations and/or three-minute short presentation about your research are optional.

Workshop organiser Professor Damien Lacroix, Chair in Biomedical Engineering, Insigneo Institute, University of Sheffield

Keynote speakers confirmed so far include:

Professor Ilaria Bellantuono, Academic Unit of Bone Biology, University of Sheffield
Dr Enrico Dall’Ara, Department of Oncology, University of Sheffield
Dr Kamar Ameen-Ali, Regional Programme Manager (North West and Yorkshire), NC3Rs – National Centre for the Replacement, Refinement and Reduction of Animals in Research

Day 2-4 Modelathon competition

The competition is based on the concept of a hackathon where different teams work on a challenging problem to ‘hack’ computer code. This event, however, uses ‘modelling’ and ‘simulation’ rather than ‘hacking’.  Our modelling competition on days 2-4 is supported by leading companies such as Ansys, Dassault SystemesSynopsys and Materialise, who will each provide hands-on support by sending an expert for the duration of the event to ensure participants utilise their company’s software to its full potential in a competitive environment.

Experience working in a team of  multi-scale professionals 

As a MultiSim Modelathon participant, you will be joining the brightest PhD and post-doctoral researchers in the field of multi-scale modelling and biomechanical engineering from around the world. Participants will be grouped into teams to try and solve a complex multi-scale modelling problem. These teams will compete against one another in front of industry and academic experts to find a solution to the assigned problem. By utilising computer simulations, participants will compete to find quicker and more effective methods of addressing musculoskeletal and cardiovascular diseases.

This is an ideal opportunity to:

  • gain practical experience of working with professionals in a multi-scale research modelling team that is likely to include clinicians and modellers;
  • enhance your computer simulation skills by using technical software on challenges based on the subject of multi-scale biomechanics in front of industry and academic experts;
  • have access to state-of-the-art techniques and software (including Abaqus, Ansys, Simpleware, Mimics, Matlab and OpenSim) as your team works through this  multi-scale challenge;
  • network and make friends in your research area;
  • win Amazon gift vouchers of £100 as a member of the winning team!

This year the challenges will be based around producing a murine in silico model to look at the effects of loading and angiogenesis on the healing process in bones. The starting point for these challenges are CT and MRI images of a mouse. Participants will gain a deeper insight into building musculoskeletal models, finite element and cardiovascular models from personalised clinical data.

 

 

Registration

Day 1
Free for all participants. This symposium can be attended as a standalone event. To help us coordinate our group discussion, on registration, please let us know of any topics you would like covered. If you intend to give a three-minute presentation on your research please provide us with the title of your talk.

Day 2-4 Modelathon competition
The fee for external participants is £108 and covers materials, refreshments, all meals and accommodation on 11,12,13 September and half day 14 September 17.
If you are attending the Modelathon competition on days 2-4 please tell us about yourself so we can ensure there is a good mix of skills in each team.  On registration you will be asked to provide information regarding:

  •  your academic background and expertise (up to 300 words)
  •  what you can bring to the Modelathon (up to 300 words)

Register at our online store by 20 August 2017 to book your place.