Preclinical assessment of bone health

Dr. Enrico Dall'Ara  presented a seminar on Preclinical assessment of bone health with longitudinal imaging and finite element modelling at INSERM institute, Lyon, France. His session was hosted by Prof Philippe Clezardin and Dr Helene Follet. Dr Dall'Ara joined the University of Sheffield in 2013 in the Department of Mechanical Engineering. His research focuses on a better ...
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Micro Finite Element models of the vertebral body: Validation of local displacement predictions

Computational models can be used to estimate the mechanical properties of bones under certain loading conditions. However, even if they are based on high-resolution micro-computed tomography (microCT) scans which provide information about the bone density and micro architecture, they need to be validated against accurate and well controlled experiments in the laboratory. In ...
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Programme set to help more under-represented teenagers reach their potential

The Brilliant Club is an award-winning charity that exists to increase the number of pupils from under-represented backgrounds progressing to highly-selective universities. They do this by mobilising the PhD community to share its academic expertise with state schools. Sofia, a PhD student on the MultiSim project at the University of Sheffield’s Insigneo Institute participat...
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Collaboration with NC3Rs to reduce animal testing

Murine-embryo-stained-for-bone-and-cartilage
University of Sheffield's researchers are trying to find ways to reduce animal testing in preclinical trials by using computer models and medical imaging. One application of this technology, also known as in silico methods, is to study the effect of skeletal diseases such as osteoporosis and its treatments.Using in silico methods, researchers conducted a longitudinal study o...
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Journal of Biomechanics: Accuracy of synchrotron based digital volume correlation for bone tissue

MultiSim's Dr Enrico Dall'Ara  talks about his paper on the accuracy of synchrotron-based digital volume correlation for bone tissue. His research was featured on the homepage of the Journal of Biomechanics edition published in July 2017. Understanding bone mechanics at different hierarchical levels is fundamental to improve preclinical and clinical assessments of bone stren...
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The University of Sheffield 3RS Symposium 2017

The University of Sheffield 3RS Symposium 2017   The University of Sheffield is hosting a 3Rs symposium on Wednesday 28 June co-organised by the NC3Rs (National Centre for the Replacement, Refinement and Reduction of Animals in Research). The aim of this event is to showcase the application of replacement, refinement and reduction (3Rs) to research u...
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Professional development for researchers

Training PDRAs at MultiSim
MultiSim has 12 post-doctoral researchers/research assistants (PDRAs). We interviewed this group to explore how they felt MultiSim has contributed to their professional development so far. The paragraphs below provide an overview of their feedback on the training opportunities we offer. Our interviews found that PDRAs actively seek new training opportunities and are self-aware ...
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The University of Sheffield 3RS Symposium 2017

Wed 28 June 10.30 am — 4.15 pm Lecture Theatre 9. The Diamond, The University of Sheffield The University of Sheffield is hosting a 3Rs symposium on Wednesday 28 June co-organised by the NC3Rs (National Centre for the Replacement, Refinement and Reduction of Animals in Research). The aim of this event is to showcase the application of replacement, refinement and...
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Andre Castro

Andre Castro is a Biomedical Engineer (MEng), who graduated from the University of Minho (Portugal, 2009). In 2011, he obtained a Post-Graduate course in Management of Health Institutions from CESPU College of Health Sciences (Portugal).  In 2013 he obtained a PhD in Biomedical Engineering (University of Minho), his thesis was on the Development of a Biomimetic Finite Element M...
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Fun, inspiring and free events at Sheffield Festival of Science and Engineering in March

Sheffield’s Festival of Science & Engineering Over 50 fun, inspiring and free events taking place during March 2017. Everyone welcome. Our Festival is celebrating world-class research in science, technology, engineering and maths (STEM), is back. This diverse programme will fascinate, entertain and engage children, young people and adults alike – with events, talks and ...
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