Pioneering workshop on the resilience of complex engineering systems hosted at the University of Sheffield

    On 18 January 2018, EPSRC’s MultiSim Frontier Engineering Award and the ENCORE network hosted a joint workshop that explored new ideas on how to use multi-scale modelling in complex engineering systems to improve resilience and function. The workshop was attended by over 50 leading engineers, statisticians, clinicians and early career researchers. As ...
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Precision of Digital Volume Correlation Approaches for Strain Analysis in Bone Imaged with Micro-Computed Tomography at Different Dimensional Levels

University of Sheffield's researchers are improving the assessment of deformation in bone tissue using "Digital Volume Correlation" (DVC) approach that is considered a state-of-the-art image-processing technique. This research aims to improve our knowledge about bone fracture mechanism. Particularly focusing on the bone fracture mechanism due to bone and joint diseases su...
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Research Associate in Computational Biomechanics

Contract Type: Fixed-term until 31 May 2019 with a start date as soon as possible Salary: £30,688 - £38,833 per annum Closing Date: 5 January 2018 How to apply? To apply visit our job pages (https://www.sheffield.ac.uk/jobs) and search for vacancy number:  UOS017913 MultiSim is a part of Insigneo Institute for in silico Medicine at the University of Sheffield. P...
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Barbara Kalkman

Barbara completed a masters in research (Human Movement Sciences) at the VU University, Netherlands. Her masters dissertation focused on neuro-muscular control of cross-educated movements. In 2014 she started a PhD at Liverpool John Moores University. Her doctoral research based in the University's Biomechanics group focused on muscle mechanical properties and the response...
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PhDs help teenagers reach their potential

The Brilliant Club is an award-winning charity that exists to increase the number of pupils from under-represented backgrounds progressing to highly-selective universities. They do this by mobilising the PhD community to share its academic expertise with state schools. Ana Sofia Ferreira,  a PhD student on the MultiSim project at the University of Sheffield’s Insigneo In...
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Preclinical assessment of bone health

Dr. Enrico Dall'Ara  presented a seminar on Preclinical assessment of bone health with longitudinal imaging and finite element modelling at INSERM institute, Lyon, France. His session was hosted by Prof Philippe Clezardin and Dr Helene Follet. Dr Dall'Ara joined the University of Sheffield in 2013 in the Department of Mechanical Engineering. His research focuses on a better ...
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Micro Finite Element models of the vertebral body: Validation of local displacement predictions

Computational models can be used to estimate the mechanical properties of bones under certain loading conditions. However, even if they are based on high-resolution micro-computed tomography (microCT) scans which provide information about the bone density and micro architecture, they need to be validated against accurate and well controlled experiments in the laboratory. In ...
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Collaboration with NC3Rs to reduce animal testing

Murine-embryo-stained-for-bone-and-cartilage
University of Sheffield's researchers are trying to find ways to reduce animal testing in preclinical trials by using computer models and medical imaging. One application of this technology, also known as in silico methods, is to study the effect of skeletal diseases such as osteoporosis and its treatments.Using in silico methods, researchers conducted a longitudinal study o...
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Journal of Biomechanics: Accuracy of synchrotron based digital volume correlation for bone tissue

MultiSim's Dr Enrico Dall'Ara  talks about his paper on the accuracy of synchrotron-based digital volume correlation for bone tissue. His research was featured on the homepage of the Journal of Biomechanics edition published in July 2017. Understanding bone mechanics at different hierarchical levels is fundamental to improve preclinical and clinical assessments of bone stren...
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