Prenatal growth map of the mouse knee joint by means of deformable registration technique

Methodological Pipeline Joint morphogenesis is the process of development of the joint that starts before the birth. It is important to study joint morphogenesis in order to understand how it is related to musculoskeletal diseases and to optimise related interventions. In several cases the interventions are tested on animal models and the mouse pre-natal model is typic...
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Collaboration with NC3Rs to reduce animal testing

Murine-embryo-stained-for-bone-and-cartilage
University of Sheffield's researchers are trying to find ways to reduce animal testing in preclinical trials by using computer models and medical imaging. One application of this technology, also known as in silico methods, is to study the effect of skeletal diseases such as osteoporosis and its treatments.Using in silico methods, researchers conducted a longitudinal study o...
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